[Info-area2] Giornata dei Dottorandi GenOMeC 2016

[FRULLANTI ELISA]

Per conto della Prof.ssa Alessandra Renieri
Coordinatore del Dottorato di Ricerca
in Genetica, Oncologia e Medicina Clinica (GenOMeC)
Dottorato Regionale Pegaso


Carissimi,

sono lieta di invitarvi alla XII edizione della Giornata dei Dottorandi 
GenOMeC 2016.

In questa giornata i dottorandi GenOMeC delle sedi di Siena, Firenze e 
Pisa presenteranno i risultati delle loro ricerche. La Giornata 
rappresenta quindi non solo un momento di valutazione dei dottorandi da 
parte del Collegio dei Docenti ma anche un'opportunità di incontro, di 
scambio e di discussione sulle tematiche di ricerca più recenti.

L'evento si terrà il 26 settembre p.v presso l'Aula Magna della 
ex-Presidenza della facoltà di Medicina dell'Università di Firenze (c/o 
Azienda Ospedaliera Universitaria Careggi, Padiglione 6, largo Brambilla 
3 - Florence).

Di seguito troverete il programma dettagliato con i diversi interventi 
dei dottorandi in modo che possiate conoscere in anticipo le tematiche 
che possono essere per voi di maggior interesse.

Cari saluti

Alessandra Renieri

--------------------------------

Programme of Annual Progress Report
Doctorate in Genetics, Oncology and Clinical Medicine (GenOMeC)
September 26, 2016

“Aula Magna ex-Presidenza” of the Faculty of Medicine and Surgery, 
University of Florence
c/o University Hospital Careggi (Padiglione 6, largo Brambilla 3 - 
Florence


Welcome Addresses
Luigi Dei, Rector of the University of Florence

9.00 	Opening
Alessandra Renieri (UniSI), Director of the Doctorate in Genetics, 
Oncology and Clinical Medicine


9.15 - 10.30	HAEMATONCOLOGY
Chairmen: Alessandro Maria Vannucchi (UniFI), Sara Galimberti (UniPI)

9.15	Cencini Emanuele, 2nd year course (Tutor: M. Bocchia, UniSI)
Study of gene polymorphisms as predictors of treatment efficacy and 
toxicity in patients with non-Hodgkin lymphomas

9.30	Corbizi Fattori Giuditta, 1st year course (Tutor: A. Vannucchi, 
UniFI)
Exploiting mutated calreticulin for diagnostic, prognostic and 
therapeutic purposes in chronic myeloproliferative neoplasms

9.45	Fanelli Tiziana, 1st year course (Tutor: A. Vannucchi, UniFI)
Clonal heterogeneity and clonal progression in the leukemic 
transformation of chronic myeloproliferative neoplasms

10.00	Grassi Susanna, 1st year course (Tutor: S. Galimberti, 
UniPI)						Pharmacogenomic, epigenetic, proteomic, and immunological 
variables as possible predictive markers of response and toxicity in 
patients affected by chronic myeloid leukemia (CML) receiving tyrosin 
kinase inhibitors (TKIs)

10.15	Poteti Martina, 1st year course (Tutor: P. Dello Sbarba, UniFI)
The metabolic profile of Chronic Myeloid Leukaemia stem cell subsets as 
a target to suppress minimal residual disease resistant to tyrosine 
kinase inhibitors


10.30-11.45	SKIN CANCERS AND MELANOMA
Chairmen: Persio Dello Sbarba (UniFI), Maresa Altomonte (AOUS)

10.30 	Giacobini Gianluca, 2nd year course (Tutor: M. Maio, AOUS)
Identification of immune correlates of clinical activity and/or disease 
outcome in melanoma patients undergoing immunotherapy or targeted 
therapy

10.45	Mancuso Pietro, 2nd year course (Tutur: A. Giordano, UniSI - A. 
Bellacosa, FCCC Philadelphia- USA)
Role of TDG in DNA demethylation and transcriptional regulation in 
melanoma

11.00	Sarti Samanta, 2nd year course (Tutor: L. Poliseno, ITT)
Assessing the biological role of miR-204 in a zebrafish melanoma model

11.15 	Tubita Alessandro, 1st year course (Tutor: P. Dello Sbarba, 
UniFI)
Targeting the Mitogen-Activated Protein Kinase ERK5 in human melanoma

11.30	Lamberti Arianna, 1st year course (Tutor: M. Fimiani, UniSI)
Genetic and molecular aspects as possible predictive clinical evolution 
of Lymphomatoid Papulosis


11.45 - 12.45	 LUNCH


12.45 - 13.15	GASTOINTESTINAL TUMORS
Chairmen: Annarosa Arcangeli (UniFI), Samantha Di Donato (Usl4-Prato)

12.45 	Iorio Jessica, 1st year course (Tutor: A. Arcangeli, UniFI)
Functional relationships between k+ channels and pH- regulating 
mechaninsms in colorectal cancer

13.00	Mori Elena, 1st year course (Tutor: P. Dello Sbarba, UniFI – A. Di 
Leo, Usl4-Prato)
Serum metabolomic profiles for discriminating early from metastatic 
disease and predicting relapse in patients with colorectal cancer


13.15 - 14.45	MOLECULAR ONCOLOGY
Chairmen: Silvo Conticello (ITT), Mario Del Rosso (UniFI)

13.15	Lofiego Maria, 2nd year course (Tutor: M. Maio, AOUS)
A new human cell-based vaccine for cancer therapy: pre-clinical 
characterization

13.30	Vitale Stefania, 1st year course (Tutor: P. Dello Sbarba, UniFI – 
A. Di Leo, Usl4-Prato)
Role of endocrine therapy in combination with anti-HER2 therapy and 
CDK4/6 inhibitors in hormone receptor positive/HER2 positive breast 
cancer

13.45 	Antonuzzo Lorenzo, 1st year course (Tutor: A. Arcangeli, UniFI)
Evaluation of expression and prognostic role of potassium channel in 
neuroendocrine pancreatic neoplasms

14.00 	Montini Marco, 1st year course (Tutor: S. Conticello, ITT)
Assaying the order of events in cells through CRISPR/Cas9

14.15	Menicacci Beatrice, 1st year course (Tutor: M. Del Rosso, UniFI)
Senescence secretory phenotype and tumor microenvironment: modulation by 
polyphenolic compounds

14.30	Astarita Carlo, 1st year course (Tutor: A. Giordano, UniFI)
Hormone imbalance promotes eye disease thought chronic cellular stress

14.45	Delaram Rahmani, 2nd year course (Tutor: A. Giordano, UniSI - I. 
Biunno, ITB-CNR Milano)
Mechanism of action of Thor in different Breast cancer cell lines 
through the expression levels
of critical cell-cycle regulators


15.00-15.15	 COFFEE BREAK


15.15 - 16.45 	MEDICAL GENETICS
Chairmen: Lucia Migliore (UniPI), Eugenia Carnevali (AOSP Terni)

15.15	Pinto Anna Maria, 2nd year course (Tutor: A. Renieri, UniSI)
Clinical and genetic studies of vascular malformations

15.30 	Landucci Elisa, 2nd year course (Tutor: F. Ariani, UniSI)
Modeling Rett syndrome with iPSCs-derived neurons

15.45	Guarnieri Giulia, 1st year course (Tutor: G. Vannelli, UniFI)
Study of genetic and epigenetic mechanisms regulating neurogenesis in 
human cholinergic neurons

16.00	Daga Sergio, 1st year course (Tutor: F. Mari, UniSI)
In vitro podocyte-like cell system: a new approach to understand Alport 
Syndrome

16.15	Stoccoro Andrea, 1st year course (Tutor: L. Migliore, UniPI)
Role of epigenetic mechanisms in mitochondrial diseases

16.30	Tommolini Federica, 1st year course (Tutor: A. Renieri, UniSI - E. 
Carnevali, AOSP Terni)
New frontiers in genetic investigation for forensic purposes: 
implementation of SNPs analysis system for predicting phenotypic traits 
(eye color) from a biological stain


16.45-17.30 	RHEUMATOLOGIC DISEASES
Chairmen: Gabriella Vannelli (UniFI), Francesca Ariani (UniSI)

16.45 	Barsotti Simone, 1st year course (Tutor: M. Mosca, UniPI)
Bone marrow mesenchymal stromal cells in an animal model of systemic 
sclerosis: characterization and potential therapeutic implications

17.00	Montella Antonio, 1st year course (Tutor: R. Nuti, UniSI - N. 
Giordano, AOUS)
In systemic sclerosis does the macrovascular damage correlate with the 
microvascular damage?

17.15	De Palma Anna, 1st year course (Tutor: M. Galeazzi, UniSI – A. 
Fioravanti, AOUS)
MicroRNAs expression after Cyclic Hydrostatic Pressure in normal and 
osteoarthritic chondrocytes cultures


17.30 Closing session and meeting of the faculty board


18.30 Attribution of credits by the faculty board



-- 
Dr. Frullanti Elisa, PhD
Medical Genetics
University of Siena, Policlinico S Maria alle Scotte
Viale Bracci, 2 - 53100 - Siena - Italy
Phone: +39 0577 233303
FAX: +39 0577 233325