<html><head><meta http-equiv="Content-Type" content="text/html charset=utf-8"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" class="">Grazie per la comunicazione,<div class="">che però mi perviene due giorni dopo la data di effetuazione dell’evento in oggetto.</div><div class="">Cordialmente,</div><div class="">Pietro Lupetti</div><div class=""><br class=""></div><div class=""><br class=""></div><div class=""><br class=""></div><div class=""><br class=""><div><blockquote type="cite" class=""><div class="">Il giorno 26 set 2018, alle ore 06:41, FRULLANTI ELISA <<a href="mailto:elisa.frullanti@unisi.it" class="">elisa.frullanti@unisi.it</a>> ha scritto:</div><br class="Apple-interchange-newline"><div class=""><div class="">PhD Day 2018<br class="">Doctorate in Genetics, Oncology and Clinical Medicine (GenOMeC)<br class="">September 26, 2018<br class=""><br class="">Room 2 of the Polo Didattico Le Scotte , University of Siena<br class="">Viale Bracci,2– Siena<br class=""><br class=""><br class="">9.00 <span class="Apple-tab-span" style="white-space:pre"> </span>Welcome Addresses<br class="">Francesco Frati, Rector of the University of Siena<br class=""><br class="">Opening<br class="">9.30 Alessandra Renieri (UniSI), Director of the Doctorate in Genetics, Oncology and Clinical Medicine<br class=""><br class=""><br class="">9.45-10.15 HAEMATONCOLOGY<br class="">Chairmen: MonicaBocchia (UniSI), Patrizia Tunici(AOUS)<br class=""><br class="">9.45 Ferrigno Ilaria, 1styearcourse (Tutor: M. Bocchia, UniSI)<br class="">Prognosticrole of isocitratedehydrogenase 1 and 2 (IDH1/IDH2) mutations in Acute MyeloidLeukemia<br class=""><br class="">10.00 Brogi Alice, 2nd year course (Tutor: V. Santini, UniFI)<br class="">Mechanisms of resistance to hypomethylating agents in MDS/AML syndromes.<br class=""><br class=""><br class="">10.15-12.00 MELANOMA AND SKIN / EYE DISEASE<br class="">Chairmen: Persio Della Sbarba (UniFi), Pietro Rubegni (UniSI)<br class=""><br class="">10.15 Anichini Giulia ,1st yearcourse (Tutor: B. Stecca, ISPRO)<br class="">Exploring the role of the sialyltransferase ST3GAL1 in melanoma<br class=""><br class="">10.30 Cannito Sara, 1st year course (Tutor: M. Maio AOUS)<br class="">Modeling of cancer immune phenotype by new epigenetic drugs: a strategy to improve efficacy ofimmunotherapy<br class=""><br class="">10.45 D’Angelo Costantino,1styearcourse (Tutor: A. GiordanoUniSI)<br class="">Evaluation of anti-proliferative and antioxidant potential of tomatoes extracts against melanoma<br class=""><br class="">11.00 Fulco Begnamino, 1st year course (Tutor: A. Giordano, UniSI)<br class="">Preventive and antiproliferative effects of tomato extracts on colorectal cancer<br class=""><br class="">11.15 Monterisi Sara, 1st year course (Tutor: M. Maio, AOUS)<br class="">Immune-remodeling activity of epigenetic drugs as bases for novel combinatorial immunotherapy clinical trials for cancer patients<br class=""><br class="">11.30 Tognetti Linda, 2nd year course (Tutor: P. Rubegni, UniSI)<br class="">Clinical and laboratory characterization of patients with localized scleroderma and response to UVA-1 phototherapy: in vivo and in vitro skin models.<br class=""><br class="">11.45 Cesari Daniele, 2nd yearcourse (Tutor: A. Giordano, UniSI)<br class="">PRMT5 as two-in-one strategy for mesothelioma treatment.<br class=""><br class="">12.00– 12.45 RHEUMATOLOGIC AND HEART DISEASES<br class="">Chairmen: AntonellaFioravanti (UniSI), Pier Leopoldo Capecchi(UniSI)<br class=""><br class="">12.00 Beltrami Matteo, 1st year course (Tutor: R. NutiUniSI),<br class="">Multimodality imaging in cardiomyopathies: correlation with genetic and pathological substrates, functional capacity, prognostic stratification and virtual modeling.<br class=""><br class="">12.15 Materozzi Maria, 2nd year course (Tutor: R. Nuti, UniSi)<br class="">Molecular biology of Paget’s Disease of Bone: role of p62 and novel genes.<br class=""><br class="">12.30 Finizola Francesco, 2nd year course (Tutor: F. LaghiPasini, UniSi)<br class="">Systemic inflammation and atrial electrical remodelling: the role of IL6-mediated changes in connexins expression.<br class=""><br class="">12.45 – 13.30 LUNG DISEASE AND TUMOR<br class="">Chairmen: Elena Bargagli(UniSI),Elisa Frullanti (UniSi)<br class=""><br class="">12.45 Bergantini Laura ,1st year course (Tutor: P Rottoli, UniSI)<br class="">Analysis of Biomarkers in Interstitial Lung Disease (ILD)<br class=""><br class="">13.00 Fui Annalisa, 1st yearcourse(Tutor: P Rottoli, UniSI)<br class="">Rituximab Therapy in Interstitial Lung Disease (ILD) associated with Rheumatoid Artrhitis (RA)<br class=""><br class="">13.15 Palmieri Maria, 1st year course (Tutor: E. Frullanti ,UniSi)<br class="">Whole exome sequencing approach in sib pairs identified oligogenic germline mutations predisposing to early lung adenocarcinoma in non-smokers<br class=""><br class="">13.30 – 14.00 LUNCH<br class=""><br class="">14.00– 15.30 MOLECULAR ONCOLOGY<br class="">Chairmen: Maria De Angioletti (ISPRO), Mario Chiariello (ISPRO)<br class=""><br class="">14.00 Cosi Irene, 2nd year course (Tutor: M. De Angioletti, ISPRO)<br class="">Transcriptional regulation and oncogenic effects of the genes deregulated by the prostate-specific expression of ETV4.<br class=""><br class="">14.15 Leonardi Margherita, 2nd year course (Tutor: M. Chiariello, ISPRO)<br class="">Activated Kinases screening identifies the IKBKEoncogene as a positive regulator of autophagy<br class=""><br class="">14.30 Laera letizia, 2nd year course (Tutor: G. Francini, UniSi – A. Di Leo, Usl4-Prato)<br class="">Exploratory investigation of serum metabolomics as predictive biomarkers of response to checkpoint inhibitors in patients with advanced non-small-cell lung cancer (NSCLC).<br class=""><br class="">14.45 Altieri Angela, 2ndyear course (Tutor: A. Giordano, UniSi)<br class="">Development of new technologies for identification of a novel proteins involved in the DNA damage response (DDR).<br class=""><br class="">15.00 Dell’Aquila Milena, 1st year course(Tutor: A. Giordano, UniSI)<br class="">Phosphoproteomic screening reveals the multiple functions of cdk9 in DNA damage response<br class=""><br class="">15.15 Dapporto Francesca, 1st yearcourse(Tutor: M. Chiariello, ISPRO)<br class="">Role of MAPK15 protein in human tumors<br class=""><br class="">15.30- 17.30 DNA AND RNA EDITING<br class="">Chairmen: Silvo Conticello (ISPRO),Francesa Mari (Unisi)<br class=""><br class="">15.30 Croci Susanna, 1st year course (Tutor: S. Giannotti, UniSi)<br class="">FOXG1 gene therapy using CRISPR/Cas9 technology and AAVs system.<br class=""><br class="">15.45 Lorenzetti Flaminia Clelia, 1st year course (Tutor: F. Mari, UniSi)<br class="">Targeting patient-specific TP53 mutations in drug-resistant Chronic Lymphocytic Leukemia (CLL) by CRISPR-Cpf1<br class=""><br class="">16.00 Lembo Gaia, 1st year course (Tutor: S. Conticello, ISPRO)<br class="">Engineering RNA editing adenosine deaminases to act on DNA<br class=""><br class="">16.15 Tarantino Danilo, 1st year course (Tutor: S. Conticello, ISPRO)<br class="">The weight of APOBEC mutations in cancer development<br class=""><br class="">16.30 Donati Francesco, 2nd year course (Tutor: S. Conticello, ISPRO)<br class="">APOBEC1 mutants to assess RNA and DNA editing component in cancer.<br class=""><br class="">16.45 Martignano Filippo, 1st year course (Tutor: S. Conticello, ISPRO)<br class="">APOBECs, mobile elements and cancer: a bioinformatic approach.<br class=""><br class="">17.00 Chieca Martina, 2nd year course (Tutor: S. Conticello, ISPRO)<br class="">Dimerization of APOBEC1 is dispensable for RNA editing.<br class=""><br class="">17.15 Di Giorgio Salvatore, 2nd yearcourse (Tutor: S. Conticello, ISPRO)<br class="">APOBEC1-dependent RNA editing, a bioinformatics approach.<br class=""><br class="">17.30 – 19.00 MEDICAL GENETICS<br class="">Chairmen: Francesca Ariani (UniSI),Lucia Migliore (UniPI)<br class=""><br class="">17.30 Catania Lorenza Maria, 2nd year course (Tutor: A. Renieri, UniSi)<br class="">Disturbance of GABA-ergic transmission in FOXG1 neurons.<br class=""><br class="">17.45 Gelli Elisa, 2nd year course (Tutor: F. Ariani, UniSi)<br class="">Splicing impact of BRCA1/2 unclassified variants.<br class=""><br class="">18.00 Paganini Irene, 2nd year course (Tutor: L. Papi)<br class="">Identification of novel schwannomatosis genes through exome sequencing<br class=""><br class="">18.15 Nicolì Vanessa, 1st year course (Tutor: L. Migliore)<br class="">Environmental factors of prenatal risk: a study on epigenetic modifications in human placentas and buccal mucosa cells of newborns.<br class=""><br class="">18.30 Gallo Roberta, 1st year course (Tutor: L. Migliore)<br class="">Methylation analysis in girls with Autism Spectrum Disorders (ASD)<br class=""><br class="">18.45 Farhad Jahanfar, 1st year course (Tutor: A. Argangeli)<br class="">High-throughput screening of analgesic compounds<br class=""><br class="">19.00 Closing session and meeting of the faculty board<br class=""><br class="">19.15 Attribution of credits by the faculty board<br class=""><br class=""><br class=""><br class="">-- <br class="">Dr. Frullanti Elisa, PhD<br class="">Medical Genetics<br class="">University of Siena, Policlinico S Maria alle Scotte<br class="">Viale Bracci, 2 - 53100 - Siena - Italy<br class="">Phone: +39 0577 233303<br class="">FAX: +39 0577 233325<br class="">Puoi gestire la tua iscrizione a questa lista tramite questa pagina: <a href="https://liste.unisi.it/listinfo/info-area2" class="">https://liste.unisi.it/listinfo/info-area2</a></div></div></blockquote></div><br class=""><div class="">
<div style="color: rgb(0, 0, 0); letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" class=""><div style="orphans: 2; widows: 2;" class="">***************************************</div><div style="orphans: 2; widows: 2;" class="">Pietro Lupetti</div><div style="orphans: 2; widows: 2;" class="">Dipartimento di Scienze della Vita</div><div style="orphans: 2; widows: 2;" class="">Università di Siena</div><div style="orphans: 2; widows: 2;" class="">Via Aldo Moro, 2 - 53100 SIENA</div><div style="orphans: 2; widows: 2;" class="">***************************************</div></div>
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